Murphy has used Caparison guitars since he was able to play guitar again after his cancer treatment. During his years with [[Death (band)|Death]], [[Obituary|Obituary]], and [[Testament|Testament]] he played [[Ibanez]] guitars, primarily the S series models, and [[B.C. Rich]] guitars during the [[Obituary]] period, especially Warlock models. He is also a longtime endorsee of [[EMG, Inc.|EMG]] pickups, and mainly uses the 85 and 89 models. For amplification he is currently using Framus Cobra series amplifiers.